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This page contains the laboratory case definition for brucellosis.

Page last updated: A type of febrile illness characterised by regular remissions or intermissions has been recognised in the Mediterranean region for centuries.

Many names have been applied to it, often relating to the localities in which it was particularly prevalent.

Malta fever, Mediterranean fever, Gibraltar fever or Rock fever and undulant fever are probably the best known.

The cause of the disease was obscure until Bruce reported numerous small coccal organisms in stained sections of spleen from a fatally infected soldier. Brucellosis is a zonosis, and with few exceptions infections in humans result from direct or indirect contact with animal sources.

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